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LGV – Lymphogranuloma Venereum

What is LGV - Lymphogranuloma Venereum ?
LGV is a bacterial sexually transmitted infection (STI) involving the lymph glands in the genital area. It is caused by a specific strain of Chlamydia trachomatis.

Who gets LGV?
The incidence is highest among sexually active people living in tropical or subtropical climates. However, recent infections have occurred among men who have sex with men (MSM) in Europe, New York City, San Francisco, Atlanta and other US cities.

How is LGV transmitted?
LGV is transmitted through unprotected anal or vaginal intercourse (without a condom).

What are the symptoms of LGV?
The first symptom may be a small, painless pimple or ulcer (sore) occurring on the penis, vagina or rectum. It is often unnoticed. It can then progress to inflamed and swollen lymph glands in the groin which may drain and bleed. Rectal symptoms can include pain and bloody or mucous discharge.

How soon do symptoms appear?
The onset of symptoms varies widely. The initial painless ulcer may appear from three to 30 days after exposure but other symptoms can take up to 6 months to appear.

When and for how long is a person able to transmit LGV?
An individual remains infectious as long as there are active (open) ulcers.

Can having LGV put a person at risk for contracting HIV?
An outbreak of LGV could increase HIV transmission. A person who has LGV and has active (open) ulcers (sores) can more easily contract HIV.

What is the treatment for LGV?
Once the infection is diagnosed a 3-week course of antibiotics is usually an effective treatment. However, the antibiotics will not reverse any damage done through infection – at times this requires surgical intervention.

What can be done to prevent LGV transmission?
• Use a male or female condom.
• Limit your number of sex partners.
• Carefully wash genitals after sexual activity.
• If you think you have LGV, avoid any sexual contact and visit your local STI clinic, a hospital or your medical provider.
• Notify all sexual contacts immediately so they can be screened for LGV.

If you are a medical provider and would like more information on LGV from the CDC, click here